Οικοδέσποινα is located in Mytilene, just a 18-minute walk from Port of Mytilene and 4 miles from Taxiarches. The property is around 1.4 miles from Fikiotripa Beach, 2.1 miles from University of the Aegean, and 7.9 miles from Saint Raphael Monastery. Free Wifi is available throughout the property and Tsamakia Beach is 1.4 miles away. Towels and bed linen are offered in the guest house. The accommodation offers an air conditioning, a heating, and a private bathroom. Popular points of interest near the guest house include Bus Station, Theophilos Museum, and Ecclesiastic and Byzantine Museum Mytilini. The nearest airport is Mytilene International Airport, 3.7 miles from Οικοδέσποινα.